https://www.selleckchem.com/pr....oducts/pf-05221304.h
Correlation analysis revealed significant positive associations between time on CPB and syndecan-1 (rs = 0.488, P less then 0.001) and level of syndecan-1 and neutrophil count (rs = 0.351, P = 0.038) at 4-8 h. Intravenous administration of recombinant syndecan-1 in mice resulted in a 2.5-fold increase in the number of circulating neutrophils, concurrent with decreased bone marrow neutrophil number. CONCLUSIONS Longer duration of CPB is associated with increased plasma levels of soluble syndecan-1, a signal for EG degradation, which
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