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The methodology is best capable of pinpoint the location of the ligand binding website than a comparable pocket detection algorithm (Pocket-Finder) on a dataset of 134 proteins. One of the strengths of the tactic is its prediction of relatively small websites. The websites have volumes roughly equal to ligand volumes irrespective of the overall measurement of the protein. This is in contrast to pocket detection, the place predicted website volumes show a much greater tendency to increase with protein size. This property would seem like a results of using probe
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