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Introduction  The number of positive cases and deaths from the coronavirus disease 2019 (COVID-19) is still increasing. The early detection of the disease is very important. Olfactory dysfunction has been reported as the main symptom in part of the patients. Objective  To analyze the potential usefulness of anosmia or hyposmia in the detection of the COVID-19 infection. Data Synthesis  We systematically searched the PubMed Central database using specific keywords related to our aims until July 31st, 2020. All articles published on COVID