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Finally, a sensitivity analysis was performed also including those patients requiring VP support for less than 6 h. RESULTS Patients subjected to VE-VPs received significantly less resuscitation fluids at vasopressor starting (0[0-510] vs. 1500[650-2300] mL, p  less then  0.001) and during the first 8 h of resuscitation (1100[500-1900] vs. 2600[1600-3800] mL, p  less then  0.001), with no significant increase in acute renal failure and/or renal replacement therapy requirements. VE-VPs was related with significant lower net fluid balanc