https://www.selleckchem.com/pr....oducts/-r-s--3-5-dhp
The present work reports two novel pharmaceutical co-crystals; 21 isoniazid-glutaric acid (INHGA) and 21 pyrazinamide-glutaric acid (PGA). Isoniazid and pyrazinamide are key first-line drugs used for the treatment of tuberculosis. The co-crystals were produced via solid-state and solvent assisted grinding methods. Thermal characteristics of the samples were obtained using the differential scanning calorimetry, hot stage microscopy, and thermogravimetric analyses. The morphology of the powder samples by scanning electron microscop