https://www.selleckchem.com/ph....armacological_epigen
In this issue of Neuron, Lahiri and Bevan (202 investigate the effects of dopamine release on striatal projection neurons. Using perforated patch recordings and optogenetics, they show that dopamine release persistently enhances the intrinsic excitability of direct pathway striatal neurons. Homeostatic plasticity rules are well described for glutamatergic synapses but less clear for GABAergic synapses. In this issue of Neuron, Pan-Vazquez et al. (202 leverage the precise targeting of chandelier-to-pyramidal cell connectiv
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