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As displayed in stability test and simulated industrial application test, CuCl2/AC has a promising industrial application prospect.The present study aimed to investigate the influence of grape seed extract (GSE) in renal toxicity, oxidative stress, and Bcl-2 expressions in Eltroxin-induced hyperthyroidism to male mice. GSE was evaluated through oral administration to male mice at dose 50 mg/kg daily for 3 consecutive weeks. Eltroxin (100 μg/kg) was administered to mice for 3 weeks, and the mice were posttreated with GSE for another 3 we