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Standard therapy bolus yielded a higher time spent in 70 to 180 mg/dL target range (mean ± standard 77% ± 27% vs physical activity-informed 59% ± 31%, = .03) yet, it was associated with a steeper negative slope in the early postprandial phase ( = .032). Use of step count to adjust mealtime insulin following a walking bout has proved to be safe and feasible in a cohort of 15 T1D subjects. Physical activity-informed insulin dosing of meals eaten soon after a walking bout has a potential of mitigating physical activity related glucose re