https://www.selleckchem.com/pr....oducts/zotatifin.htm
TMEM106B expression was upregulated by 2-fold in CAD coronary arteries. A significant association was found between variants in TMEM106B (but not in TMEM10 and CAD (P=1.9×10-8). Significant gene-gene interaction was detected between ANRIL variant rs2383207 and TMEM106B variant rs3807865 (P=0.009). A similar approach also identifies significant interaction between rs6903956 in ADTRP and rs17465637 in MIA3 (P=0.005). Conclusions We demonstrate 2 pairs of epistatic interactions between GWAS loci for CAD and offer important insights
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