https://www.selleckchem.com/products/GDC-0449.html
Sevoflurane postconditioning (SPostC) is proved effective against myocardial cardioprotection injury. It has been reported that heat shock protein 70 (HSP7 could be induced by sevoflurane, which played a crucial role in hypoxic/reoxygenation (HR) injury of cardiomyocytes. The mechanism of sevoflurane to protect cardiomyocytes via HSP70 is still understood. We aimed to investigate the related mechanisms of SPostC inducing HSP70 expression to reduce the HR injury of cardiomyocytes. After HR cardiomyocytes model was established, the cel
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