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To improve the patient's adaptation, psychological interventions such as short-term psychotherapy, cognitive behavioral therapy, mindfulness meditation, biofeedback, and group psychotherapy can be helpful. ( L.), ( C.B. Clarke), ( L.) and ( L.) have been selected for this study as they have been associated with medicinal actions for litholytic activity. The experiment was carried out in Sprague Dawley rats divided into seven groups, serving as plain control, disease control, standard control, curative A and B and preventive A and B group